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Viser: Chemical Sciences in Early Drug Discovery - Medicinal Chemistry 2. 0
Chemical Sciences in Early Drug Discovery Vital Source e-bog
Pierfausto Seneci
(2018)
Chemical Sciences in Early Drug Discovery
Medicinal Chemistry 2. 0
Pierfausto Seneci
(2018)
Sprog: Engelsk
Detaljer om varen
- Vital Source searchable e-book (Reflowable pages)
- Udgiver: Elsevier Science (Juni 2018)
- ISBN: 9780080999289
Chemical Sciences in Early Drug Discovery: Medicinal Chemistry 2.0 describes how new technologies and approaches can be used to improve the probability of success in fulfilling the perennial goal of finding and developing new drugs. Drawing on the author's extensive experience consulting and teaching in medicinal chemistry, the book outlines ways in which medicinal chemistry is widening its reach to meet modern demands, and how modern technologies and approaches are facilitating this growth into new fields. Supported by examples throughout, the book is a practical resource for organic-medicinal chemists, biological chemists and pharmacologists involved in drug discovery.
- Reviews the key application of chemistry in drug discovery for both medicinal and non-medicinal chemists, clarifying and explaining the role of medicinal chemistry in supporting the modern drug discovery pipeline
- Shows how a wider medicinal chemistry view is essential for anyone in an integrated drug discovery project looking to reduce costs and save time
- Provides the critical success factors needed to successfully identify hits from both biological and chemical perspectives
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Detaljer om varen
- Paperback: 200 sider
- Udgiver: Elsevier (Juni 2018)
- ISBN: 9780080994208
Chemical Sciences in Early Drug Discovery: Medicinal Chemistry 2.0 describes how new technologies and approaches can be used to improve the probability of success in fulfilling the perennial goal of finding and developing new drugs. Drawing on the author's extensive experience consulting and teaching in medicinal chemistry, the book outlines ways in which medicinal chemistry is widening its reach to meet modern demands, and how modern technologies and approaches are facilitating this growth into new fields. Supported by examples throughout, the book is a practical resource for organic-medicinal chemists, biological chemists and pharmacologists involved in drug discovery.
- Reviews the key application of chemistry in drug discovery for both medicinal and non-medicinal chemists, clarifying and explaining the role of medicinal chemistry in supporting the modern drug discovery pipeline
- Shows how a wider medicinal chemistry view is essential for anyone in an integrated drug discovery project looking to reduce costs and save time
- Provides the critical success factors needed to successfully identify hits from both biological and chemical perspectives
1: Target Identification
2. Step II: Target Validation
3. Step IIIa: Biological Hit Discovery Through High-Throughput Screening (HTS): Random Approaches and Rational Design
4. Step IIIb: The Drug-Like Chemical Diversity Pool: Diverse and Targeted Compound Collections
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