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Viser: Signal Transduction

Signal Transduction, 3. udgave
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Signal Transduction Vital Source e-bog

Ijsbrand M. Kramer
(2015)
Elsevier Science
895,00 kr.
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Signal Transduction, 3. udgave

Signal Transduction

ljsbrand M. Kramer
(2015)
Sprog: Engelsk
Elsevier Science & Technology
1.162,00 kr.
Print on demand. Leveringstid vil være ca 2-3 uger.
Denne bog erstatter Signal Transduction, 2. udgave

Detaljer om varen

  • 3. Udgave
  • Vital Source searchable e-book (Reflowable pages): 1104 sider
  • Udgiver: Elsevier Science (Oktober 2015)
  • ISBN: 9780123948199

Signal Transduction, Third Edition is a thorough, well-illustrated study in cellular signaling processes. Beginning with the basics, this book shows how cells respond to external cues, hormones, growth factors, cytokines, cell surfaces, etc., and further instructs how these inputs are integrated.

Instruction continues with up-to-date, inclusive coverage of intracellular calcium, nuclear receptors, tyrosine protein kinases and adaptive immunity, and targeting transduction pathways for research and medical intervention. This book will serve as an invaluable resource for advanced undergraduates, graduate researchers, and established scientists working in cell biology, pharmacology, immunology, and related fields.



  • Includes up-to-date, inclusive coverage of targeting transduction pathways for research and medical intervention
  • Provides in-depth coverage of nuclear receptors, including steps in isolation of steroid hormones and the discovery of intracellular hormone receptors, tyrosine protein kinases and adaptive immunity, and intracellular calcium
  • Presents extensive conceptual color artwork to assist with comprehension of key topics
  • Includes instrumental margin notes that highlight milestones in signaling mechanisms
Licens varighed:
Bookshelf online: 5 år fra købsdato.
Bookshelf appen: ubegrænset dage fra købsdato.

Udgiveren oplyser at følgende begrænsninger er gældende for dette produkt:
Print: -1 sider kan printes ad gangen
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Detaljer om varen

  • 3. Udgave
  • Hardback: 1104 sider
  • Udgiver: Elsevier Science & Technology (December 2015)
  • ISBN: 9780123948038

A reference on cellular signaling processes, the third edition of Signal Transduction continues in the tradition of previous editions, in providing a historical overview of how the concept of stimulus-response coupling arose in the early twentieth century and shaped our current understanding of the action of hormones, cytokines, neurotransmitters, growth factors and adhesion molecules. In a new chapter, an introduction to signal transduction, the book provides a concise overview of receptor mechanisms, from receptor - ligand interactions to post-translational modifications operational in the process of bringing about cellular changes. The phosphorylation process, from bacteria to men, is discussed in detail.

Signal transduction third edition further elaborates on diverse signaling cascades within particular contexts such as muscle contraction, innate and adaptive immunity, glucose metabolism, regulation of appetite, oncogenic transformation and cell fate decision during development or in stem cell niches. The subjects have been enriched with descriptions of the relevant anatomical, histological, physiological or pathological condition.

  • In-depth insight into a subject central to cell biology and fundamental to biomedicine, including the search for novel therapeutic interventions
  • Essential signaling events embedded in rich physiological and pathological contexts
  • Extensive conceptual colour artwork to assist with comprehension of key topics
  • Special emphasis on how molecular structure determines protein function and subcellular localization
  • Employment of unambiguous protein names (symbols) in agreement with leading protein- and gene databases, allowing the learner to extend his/her exploration on the web
1. Prologue: Signal Transduction from a Historical Perspective2. An Introduction to Signal Transduction3. Regulation of Muscle Contraction by Receptors4. Cholinergic Signaling and Muscle Contraction5. Sensory Signal Processing; Visual Transduction and Olfaction6. Intracellular Calcium7. Bringing the Signal into the Nucleus: Regulation of Gene Expression8. Nuclear Receptors9. Protein Kinase C and Oncogenic Transformation and Cell Polarity10. Regulation of Cell Proliferation by Receptor Tyrosine Protein Kinases11. Signal Transduction to and from Adhesion Molecules12. WNT Signaling and the Regulation of Cell Adhesion and Differentiation13. Activation of the Innate Immune System: the Toll-Like Receptor-4 and Signaling through Ubiquitylation14. Chemokines and Traffic of White Blood Cells15. Activating the Adaptive Immune System: Role of Non-receptor Tyrosine Kinases16. Signaling through the Insulin Receptor: Phosphoinositide 3-Kinases and AKT17. TGFß and Signaling through Receptor Serine/Threonine Protein Kinases18. Protein Phosphates19. Cell Fate Determination by Notch
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