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Viser: An Introduction to Systems Biology

An Introduction to Systems Biology, 2. udgave

An Introduction to Systems Biology Vital Source e-bog

Uri Alon
(2019)
Taylor & Francis
657,00 kr. 591,30 kr.
Leveres umiddelbart efter køb
An Introduction to Systems Biology, 2. udgave

An Introduction to Systems Biology

Uri Alon
(2019)
Sprog: Engelsk
CRC Press LLC
620,00 kr. 558,00 kr.
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Detaljer Om Varen

  • 2. Udgave
  • Vital Source E-book
  • Udgiver: Taylor & Francis (Juli 2019)
  • ISBN: 9781000008166
Praise for the first edition: … superb, beautifully written and organized work that takes an engineering approach to systems biology. Alon provides nicely written appendices to explain the basic mathematical and biological concepts clearly and succinctly without interfering with the main text. He starts with a mathematical description of transcriptional activation and then describes some basic transcription-network motifs (patterns) that can be combined to form larger networks. – Nature [This text deserves] serious attention from any quantitative scientist who hopes to learn about modern biology … It assumes no prior knowledge of or even interest in biology … One final aspect that must be mentioned is the wonderful set of exercises that accompany each chapter. … Alon’s book should become a standard part of the training of graduate students. – Physics Today Written for students and researchers, the second edition of this best-selling textbook continues to offer a clear presentation of design principles that govern the structure and behavior of biological systems. It highlights simple, recurring circuit elements that make up the regulation of cells and tissues. Rigorously classroom-tested, this edition includes new chapters on exciting advances made in the last decade. Features: Includes seven new chapters The new edition has 189 exercises, the previous edition had 66  Offers new examples relevant to human physiology and disease The book website including course videos can be found here: https://www.weizmann.ac.il/mcb/UriAlon/introduction-systems-biology-design-principles-biological-circuits.
Licens varighed:
Online udgaven er tilgængelig: 365 dage fra købsdato.
Offline udgaven er tilgængelig: ubegrænset dage fra købsdato.

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Print: 2 sider kan printes ad gangen
Copy: højest 2 sider i alt kan kopieres (copy/paste)

Detaljer Om Varen

  • 2. Udgave
  • Paperback: 324 sider
  • Udgiver: CRC Press LLC (August 2019)
  • ISBN: 9781439837177

Praise for the first edition:

... superb, beautifully written and organized work that takes an engineering approach to systems biology. Alon provides nicely written appendices to explain the basic mathematical and biological concepts clearly and succinctly without interfering with the main text. He starts with a mathematical description of transcriptional activation and then describes some basic transcription-network motifs (patterns) that can be combined to form larger networks. - Nature

[This text deserves] serious attention from any quantitative scientist who hopes to learn about modern biology ... It assumes no prior knowledge of or even interest in biology ... One final aspect that must be mentioned is the wonderful set of exercises that accompany each chapter. ... Alon's book should become a standard part of the training of graduate students. - Physics Today

Written for students and researchers, the second edition of this best-selling textbook continues to offer a clear presentation of design principles that govern the structure and behavior of biological systems. It highlights simple, recurring circuit elements that make up the regulation of cells and tissues. Rigorously classroom-tested, this edition includes new chapters on exciting advances made in the last decade.

Features:

  • Includes seven new chapters
  • The new edition has 189 exercises, the previous edition had 66 
  • Offers new examples relevant to human physiology and disease

Part One: Network Motifs
Chapter 1. Transcription Networks basic concepts
Chapter 2. Autoregulation
Chapter 3. The Feed Forward Loop
Chapter 4. Temporal Programs and the Global Structure of Transcription Networks
Chapter 5. Positive Feedback, Bistability and Memory
Chapter 6. How to Build a Biological Oscillator

Part Two: Robustness
Chapter 7. Kinetic Proofreading and Conformational Proofreading
Chapter 8. Robust Signalling
Chapter 9. Chemotaxis
Chapter 10. Fold-change Detection
Chapter 11. Dynamical Compensation and Mutal Resistance in Tissues
Chapter 12. Robust Spatial Patterning in Development.

Part Three: Optimality
Chapter 13. Optimal Gene Circuit Design Chapter14. Multi-objective Optimality in Biology
Chapter 15. Modularity

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