Viser: DNA-Encoded Library Technology for Drug Discovery

DNA-encoded Library Technology for Drug Discovery, 1. udgave
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DNA-encoded Library Technology for Drug Discovery Vital Source e-bog

Guansai Liu
(2025)
Royal Society of Chemistry
2.374,00 kr.
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DNA-Encoded Library Technology for Drug Discovery

DNA-Encoded Library Technology for Drug Discovery

Guansai Liu, Casey J. Krusemark og Jin Li
(2025)
Sprog: Engelsk
Royal Society of Chemistry, The
2.742,00 kr.
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Detaljer om varen

  • 1. Udgave
  • Vital Source searchable e-book (Reflowable pages)
  • Udgiver: Royal Society of Chemistry (Februar 2025)
  • ISBN: 9781839160554
DNA-encoded libraries have numerous advantages over traditional screening methods, including easy identification of compounds and the large quantity of compounds that can be screened simultaneously. This book provides a comprehensive guide to the implementation of DNA-encoded library technology (DELT) in drug discovery for screening and hit validation, illustrated with successful case studies. A valuable resource for researchers in drug discovery, this book is complete with successful case studies to illustrate the best practice in implementation and operation of DELT.
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Detaljer om varen

  • Hardback: 176 sider
  • Udgiver: Royal Society of Chemistry, The (Februar 2025)
  • Forfattere: Guansai Liu, Casey J. Krusemark og Jin Li
  • ISBN: 9781788014878

DNA-encoded libraries have numerous advantages over traditional screening methods, including easy identification of compounds and the large quantity of compounds that can be screened simultaneously.

This book provides a comprehensive guide to the implementation of DNA-encoded library technology (DELT) in drug discovery for screening and hit validation, illustrated with successful case studies.

A valuable resource for researchers in drug discovery, this book is complete with successful case studies to illustrate the best practice in implementation and operation of DELT.

Overview of Affinity-based DEL Selections with Select Target Types and Achievements Machine Learning with DEL Selection Data and for DEL design One bead one compound (OBOC) DELs for Biochemical Screens Live cell-based DEL Selections On-DNA Medicinal Chemistry: Focused libraries, fragment expansion, and hit optimization DELs with Covalent Warheads Application of DELs for E3 Ligase Ligand and PROTAC development

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