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Section I Introduction and Background 1 What is sensitive skin? Renée J.H. Richters, Natallia E. Uzunbajakava, Piet E.J. van Erp, and Peter C.M. van de Kerkhof 2 Sensitive skin: a review of prevalence worldwide Charles Taieb and Laurent Misery 3 Skin structure and function Golara Honari 4 The somatosensory system Francis McGlone and David Reilly Section II Pathophysiology of Sensitive Skin 5 Stratum corneum and sensitive skin Enzo Berardesca 6 Altered somatosensory pathways Eun Ju Kim, Dong Hun Lee, and Jin Ho Chung 7 Itch and sensitive skin Martin Schmelz Section III Investigative Methods 8 Challenges of investigation Lidia Maroñas-Jiménez, Elena González-Guerra, and Aurora Guerra-Tapia 9 Self-assessment of sensitive skin Charles Taieb and Laurent Misery 10 Confocal Raman Micro-Spectroscopy: a new paradigm in the diagnosis of sensitive skin? Denise Falcone, Natallia E. Uzunbajakava, Piet E.J. van Erp, and Peter C.M. van de Kerkhof 11 Regarding the quantification of the human skin barrier in Sensitive Skin Syndrome Luís Monteiro Rodrigues, Henrique Silva, and Catarina Rosado 12 Irritant reactivity tests David A. Basketter 13 Neurosensory assessment Roland Jourdain Section IV Clinical Considerations 14 Sensitive skin: there is a link with ethnicity? Laurent Misery and Charles Taieb 15 Gender and age influence on sensitive skin Rosa Marie Andersen 16 Sensitive skin: do we observe an impact on quality of life? Laurent Misery and Charles Taieb 17 Perceived sensitive skin at different anatomic sites Miranda A. Farage 18 Sensitive skin and non-eczematous dermatoses Ian McDonald, Helen Rea, and Martin Steinhoff 19 Sensitive skin and eczematous dermatoses Arun C Inamadar and Aparna Palit Section V Environmental Factors and Everyday Products 20 Influence of air pollution on skin Sparsha Saxena and Golara Honari 21 Sensitive skin, skin care products and cosmetics Enzo Berardesca 22 Fabrics and sensitive skin Gerald E. Pierard and Howard I. Maibach Section VI Management 23 Dermatotoxicology and sensitive skin syndrome Golara Honari and Howard I. Maibach 24 Formulations for sensitive skin Golara Honari and Howard I. Maibach 25 Treatments for sensitive skin Martina Kerscher and Heike Buntrock Index

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