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Viser: An Introduction to Systems Biology - Design Principles of Biological Circuits
An Introduction to Systems Biology
Design Principles of Biological Circuits
Uri Alon
(2006)
Sprog: Engelsk
CRC Press LLC
723,00 kr.
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Detaljer om varen
- 1. Udgave
- Paperback: 320 sider
- Udgiver: CRC Press LLC (Juli 2006)
- ISBN: 9781584886426
Thorough and accessible, this book presents the design principles of biological systems, and highlights the recurring circuit elements that make up biological networks. It provides a simple mathematical framework which can be used to understand and even design biological circuits. The textavoids specialist terms, focusing instead on several well-studied biological systems that concisely demonstrate key principles.
An Introduction to Systems Biology: Design Principles of Biological Circuits builds a solid foundation for the intuitive understanding of general principles. It encourages the reader to ask why a system is designed in a particular way and then proceeds to answer with simplified models.
Transcription Networks, Basic Concepts. Auto-Regulation, a Network Motif. The Feedforward Loop Network Motif. Temporal Programs and the Global Structure of Transcription Networks. Network Motifs in Developmental, Signal-Transduction and Neuronal Networks. Robustness of Protein Circuits, the Example of Bacterial Chemotaxis. Robust Patterning in Development. Kinetic Proofreading. Optimal Gene Circuit Design. Rules for Gene Regulation Based on Error Minimization. Epilogue. Appendices. Glossary. Bibliography.
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